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KMID : 0978920020030030053
Korean Journal of Clinical Geriatrics
2002 Volume.3 No. 3 p.53 ~ p.61
The clinical characteristics of patients with silent stroke
Kim Do-Hoon

Moon Yoo-Sun
Abstract
Background : It has been reported that silent stroke has been commonly found in the elderly. Silent cerebral infarction (SCI) implicates the possibility of cerebrovascular lesions, which are also suggestive of having risk factors for geriatric depression, decrease in cognitive function, cerebral infarction and vascular dementia. This study investigated prevalence and clinical characteristics of patients with silent cerebral infarctions on brain CT (computed tomography) in normal healthy adults.

Method: 193 adults above age of 20 were studies who took health examinations for the regular health screening from 1998 to 2001 in Chuchon Sacred Heart Hospital. All subjects filled out Zung¡¯s depression scale (SDS) for the evaluation of depressive symptoms. Past histories of hypertension, smoking, alcohol drinking, and height, body weight, BMI (body mass index), systolic and diastolic blood pressure, fasting blood sugar, serum lipids (cholesterol, triglyceride, LDL-C, HDL-C) were evaluated in all subjects. The subjects were divided into two group (SCI group and normal control group) and student t test or ¥ö©÷ tests were carried out with the significance level of 0.05.

Results and Conclusion : SCI on CT were found in relatively old age groups, and hypertension histories were more frequent in SCI group and systolic and diastolic blood pressures were higher in SCI groups. Serum LDL-C levels were higher in SCI group than normal control group. The amount of alcohol drinking, smoking and BMI index were not significantly different between two groups. Normal healthy adults with SCI on CT should be followed up for long period of time to investigate incidence of clinical infarct and depressive symptoms and change in cognitive function.
KEYWORD
Silent stroke, Silent cerebral infarc, Computed tomography (CT), Old age, Hypertension
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